User Name Password Remember Me  
 
 
   
Video Podcast
Audio Cast
Mobile(WAP)
  Pedi Poll  
Is childhood obesity on the rise? Are children becoming fatter?
Yes
No
  Translate This Page  
 
SPECIALIST ANSWERS

Question

Jyoti, eight and half years old female child was brought to me with following positive points and investigations: Consanguineous parents ( father and mother were real cousins before marriage) Yellow eyes, anasarca with ascites, red urine ( duration 1 month) with ? burning micturition Past history of hospitalization before five years for fever with altered sensorium –recovered smoothly and completely Family history of consanguinity Two previous male sibs died. First at 7 years age. Cause not known. But he had some ?renal problem at the time of death. Second male sib died at 13 years age with ?chronic liver disease.(papers are not available). Third male sib has mental retardation with gait disturbances. she has apparently normal male sibs, one 23 year old and another 11 years old. On examination , Temp normal . pulse 108/min,BP 130/70 mmof Hg Yellow sclera, anemia, anasarca, ascites, liver 1.5 cm and spleen 1 cm below costal margin Conscious alert awake ,not looking ill Investigations, Hb 9.9 TC 12,100 s.bil total 1.9 ( normal upto 1.2) direct 1.4 ( normal upto 0.4) indirect 0.5 (normal 0.1 to 1.0) SGPT 82 , s. alk phosphatase normal s. protein total 6.1, albumin 2.76, globulin 3.39 bl sugar random 170 urine albumin trace, urine sugar ++ ( child had sugarcane juice prior to urine report but not prior to blood reports), pus cells 13 /hpf and plenty of RBCs/hpf USG abdomen showing right renal and ureteric calculus with mild hydronephrosis with hydroureter. Our further plans: Urine for metabolic screening Bl urea creatinine Liver viral serology and wilson’s disease profile Are we dealing with genetic / metabolic disorder? Can u guide us further?

Answer

The child has a chronic liver disease with renal calculi. The calculi itself could be leading to hematuria and hydronephrosis which in turn could be leading to renal dysfunction and hypertension.
One can think of following possiblities to explain both etiologies:
Porphyria
Chronic liver disease leading to oxalate malabsorption and oxaluria leading to oxalate stone
Polycystic kidney disease.
One can do 24 hours urine for calcium, oxalate, uric acid to determine the kind of stone and if unrelated then both liver disease and renal disease may be unrelated.
For liver disease, do viral markers, autoimmune tests, wilsons workup, alpha 1 antitrypsin deficiency, cystic fibrosis and metabolic workup for tyrosinemia and fructosemia.
  Grants  
 » Apply For Research Grant
  Search  
Hospitals
Pediatrician
Special Schools
Medical Colleges
Pediatric Residency
Pediatric Conferences
Jobs & Vacancies
Journals
NGO's
  Ped Tools  
Pediatric Calculator
Drug Index
Medical Equipment
Vaccine Reminder
Adverse Drug Reactions
Biochemical Profile
Online MCQ's
  Calculators  
+ Growth
+ Conversion
+ Renal
+ Pregnancy
+ Blood Pressure
+ Blood Group
+ Critical Care
+ Drug Dose
+ Diarrhea Solution
+ Reference Values
+ Antibody Test
+ Drug Interaction
 
 
Parent Corner l Kids Corner l Terms & Condition | Privacy Statement l Advertising l Feedback l Awards
About Us
l Link to Us l Site Map l Shopping Mall  
Partner Sites
 HIV in Children  Infection in Children  Pedcall  Medical ADRIS  Vaccine Reminder  Pediatric Oncall Journal

Copyright© 2000-2008 All rights reserved with Pediatric Oncall

Disclaimer:The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitue an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.

 
Sitemap For Doctor | Sitemap For Parent | Sitemap For Kids Site designed and maintained by Levioza