4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
3 month old male child of nonconsanguinity was presented with tonic convulsions with no neck control till time. Routine investigations for convulsions are normal. CT scan of the brain showed frontotemporal atrophy, how is that significant at this age?. S.ammonia is also 3 times the normal value. Convulsions were under control with 3 drugs.
Answer
An MRI would be warranted as CT scan may not be very specific. It is imperative to know whether there are any white or grey matter changes? Also what is the birth history and birth weight? Family history is also necessary. Is the ammonia high prior to the start of the anticonvulsants or after adding the ACT. Ammonia may increase following valproate. If ammonia is persistently high, one must rule out metabolic disorders and do serum electrolytes, blood gas, blood sugar and urine organic acids. Also EEG is a must.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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