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| SPECIALIST ANSWERS
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Question |
An infant presenting with Acute upper respiratory tract infection and accompanying vomiting and lethargy. Upper respiratory symptoms subsided but vomiting persisted. Family history was not contributory. There is a doubtful history of contact with Tuberculosis. On examination, the baby was found afebrile with hepatosplenomegaly, vaginal candidiasis. On investigations, the child was found to have ketonuria and glycosuria with euglycemia. Blood picture showed microcytic hypochromic anemia with thrombocytosis and lymphocytosis. Serum uric acid was normal but triglycerides were increased with normal cholesterol. ESR was 6 mm/in first hour. What are the differential diagnosis for this kind of picture?
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Answer |
Rule out diabetes mellitus especially since the child was vomiting, lethargic with ketonuria and glycosuria (diabetic ketoacidosis). With vaginal candidiasis, polyendocrinopathy with muco-cutaneous candidiasis seems the likely diagnosis.
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