4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
I have a 10 years old white male with 5 day history of severe abdominal pain, a febrile with negative exam, specifically no rash. FH dad with history of kidney transplant due to glomerulonephritis and a history of renal stones. Child had TNTC red cells. No proteinuria. H/H 41.9/15 smear revealed a few microcytes and mild poikilocytosis. MCV 79 platelets 345K. BUN 10, Creatinine 0.5. Calcium 7.5, ionized Calcium 3.18, Magnesium 2.28, Phosphate 5.3. Albumen 4.9, globulin 7.4. CT of abdomen and pelvis with and without contrast neg for hydronephrosis or calcification. Any ideas on differential diagnosis and suggestion for further workout??.
Answer
One may need to know more details on the type of glomerulonephritis in the father as conditions such as IgA nephropathy, Alports syndrome may be familial. Since the child has severe abdominal pain and was with a significant family history and RBCs in urine, one may want to rule out familial glomerulopathies such as Alports syndrome. If we ignrore the family history, conditions such as Porphyria should also be kept in mind.
 
 
 
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