Lymphadenopathy - Pediatric Oncall

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

Diagnostic Dilemma

Clinical Tools

Clinical Vignettes

Diseases & Conditions

Drugs Interaction Calculator

Podcasts

Patient Management Online

Diagnostic Dilemma

Question of the Day

Medical Quiz

Interactives

Ask Queries

SPECIALIST ANSWERS

Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

Video Podcast

Videos in Medicines

Medical Training Videos

Clinical Video Resource

Videos on Asthma

Audio Cast

Lecture on Pediatrics

Medical Training Audios

Clinical Audio Resources

Audios on Asthma

Mobile (wap)

Staying connected to Pediatric Oncall is now easier with Pediatric Oncall Mobile . You can now download selected content from the latest issue of Pediatric Oncall.

Research Grant

FIND DIAGNOSIS

VACCINE REMINDER

Get the Vaccine Schedule for your child."

	Specialist Answers
Question
Dear sir a young couple closely related to each other has a big problem. They have 6 children 3 alive & 3 died due to unknown cause. Those children who died usually had problem at the age 4-6month. They suffered from a chest infection which is resistant to treatment. Those who died were male & female both. The 1st died at 4m, 2nd died at 6m, 3rd died 2year after a protracted course of illness started as LRT infection & lymphadenopathy . The age of the alive children are 8years (female) , 3years(female), 18months(male).The 1st & 3rd are totally normal.The 2nd child ie 3year(female) run the same illness LRT infection , lymphadenopathy, FTT progress to chronic lung disease + clubbing of finger+ chronic exuding ,fascial widespreading skin infection . Those who died & this patient. are fully vaccinated ,while those survived are not vaccinated . On examination chronically ill child was under weight dyspenic with + clubbing of fingers Vital sign are normal apart from tachypenia. Generalized lymphadenopathy, Resp. system: bilateral rhonchi & crepition Cvs. System: normal Soft abdomen, mild hepatosplenomegaly Investigation: CBC was normal GOT+GPT normal. Blood urea & creatinin was normal Immunoglobulin assay showed normal ESR 50. Sweat test was normal Toxoplasmosis titer: -ve Blood , urine, stool culture are Ã¢â‚¬â€œve Tt reaction Ã¢â‚¬â€œve ACE normal Sputum for Tb bacilli Ã¢â‚¬â€œve Gastric aspirate for Tb bacilli Ã¢â‚¬â€œve Bone scan was normal. Abdominal sonar was normal Cxr & CAT scan chest infection & hilar lymphadenopathy +lung fibrosis. Lymph node & lung biopsy :Follcular hyperplastic lymphadenitis with evidence of progressive transformation of germinal centers & occasional mini clusters of epitheloid & giant cells without true granuloma formation or caseation necrosis. This is most consistent with: a. progressive transformation of germinal centers. b. Toxoplasmosis & other specific(none-Tb) infection. The skin lesion as seen by an expert dermatologist to be mostly as Tb of skin. What is your opinion about this case? Waiting your advice.
Answer
What is serum IgE? Also is there persistent neutrophilia. One should rule out Hyper IgE and Chronic granulomatous disease. A serum IgE level, NBT test and peripheral smear for neutrophil granules is advisable. Back to All Questions

Diseases & Conditions

Pediatric Oncall Journal

Pediatric Conferences

Ped Tools

Adverse Drug Reactions

Head circumference Calculator

Mid parental height Calculator

Body surface area Calculator

BMR Calculator

Temperature Calculator

Anion gap Calculator

Today's Poll

Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

Vote

Results

Pediatric oncall book store

Partner Sites

Infection in Children

Pedcall

Medical ADRIS

Vaccine Reminder

Pediatric Oncall Journal

Educational Section

Disclaimer:

The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.

Sitemap For Doctor

Sitemap For Parent

Sitemap For Kids