4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
A 6 years old male presented with fever followed by swelling of the face, within 24 hours which was followed by necrotising lesion of the nasal cavity extending to the periorbital and ethmoid,maxillary and sphenoid sinus. There is no significant past history of repeated infections, chronic nasal discharge, or contact with T.B, No history S/O immunodeficiency or diabetes mellitus. There is history of 4 sibling sudden deaths in infancy, without any prior illness, cause not known. On examination there was crusted lesion with destruction of nasal septum with periorbital swelling. Please suggest some differential diagnosis and the most likely diagnostic possibility.
Answer
A culture of the lesion is required. Apart from bacterial infections, infections such as mucormycosis and aspergillosis should be kept in mind. If fungal cultures are positive, an underlying immunodeficiency should be ruled out.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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