4th Pediatric Infectious Diseases Conference
 
 
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Autoimmune Disorder
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Specialist Answers
Question
Sir, I am an asst. professor medicine at MKCG medical college, berhampur orissa. My daughter has been suffering from musculo skeletal pain with recurrent UTI for last 8 months. She is 10 years old. She has been investigated for SLE at Vellore in December. The tests negative for SLE. Now she has UTI again with skin lesions diagnosed as nodular vasculitis. Kindly advice me what steps to be taken for the diagnosis You can suggest name of consultants or institutions. Yours sincerely.
Answer
Urinary tract infections or UTI usually are diagnosed by urine culture and microscopy. However, if your child has nodular vasculitis and test for SLE such as ANA, dsDNA are negative, then other autoimmune conditions such as polyarteritis nodosa (PAN) or pauci-immune vacsculitis should be ruled out. You may require to do other tests such as ANCA, C3 complement levels and maybe even a skin biopsy of the lesion. You can take her to any of the tertiary institutes such as AIIMS in Delhi, Calcutta or even Mumbai where there are tertiary referral centers with good pediatric nephrology and immunology departments.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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