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SPECIALIST ANSWERS
Question
Does oral formulation of Ofloxacin causes raised intracranial tension as is seen with Nalidixic acid ?Whether Nalidixic acid comes under quinoline group?
Answer
There have been reports of raised intracranial tension after the use of oral quinolones (Ref:
1. Arch Dis Child 1990 Oct;65(10):1165-1166,
2. Acta Neurol Scand 1993 Jun;87(6):503-4)

This is due to Nalidixic acid found in some quinolone drugs.
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