Aciclovir Use in A Patient With Varicella

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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	Specialist Answers
Question
How does aciclovir help a patient with varicella? Does it prevent herpes zoster? 2. Is ivermectin-albendazole combination rational? 3. In Rti cefixime or cefpodoxime, which molecule is superior? 4. Should I give OPV\IPV to all patients?
Answer
1. Read the article on VARICELLA ZOSTER VIRUS on www.pediatriconcall.com or from the link given below: http://www.pediatriconcall.com/fordoctor/DiseasesandCondition/ infectious_diseases/varicellazoster.asp 2. Ivermectin is contraindicated in children <5 years of age. It is used in treatment of Onchocerciasis, Filariasis, Strongyloidosis, Norwegian scabies. Albendazole is an anthelmintic. For more details read the DRUG INDEX on www.pediatriconcall.com or from the link given below: http://www.pediatriconcall.com/fordoctor/DrugsandMedical/ alphabeticaldruglinks.asp 3. Cefpodoxime proxetil is an orally administered extended spectrum, semi-synthetic antibiotic of the cephalosporin class. Cefixime has predominantly gram negative coverage (cefixime has poor efficacy against staphylococcus and streptococci) but has also been found useful in respiratory infection. However Cefpodoxime proxetil is a well tolerated and superior alternative to the earlier oral third generation cefixime for LRTIs in children. The cost is the major deterrant. 4. OPV has not shown herd effectiveness it has failed to protect non-immunized children in UP and Bihar or for that matter anywhere in the country (and has even failed to protect some who have received more than adequate number of OPV doses). This means that one needs to achieve near 100% coverage during routine immunization and SIAs with OPV. This is nearly impossible. In addition, one needs to give a staggering 10-15 doses of OPV in UP and Bihar for individual protection with OPV, that too as early in life as possible, preferably before the age of 6-12 months to interrupt wild poliovirus transmission. IPV is known to lead to 95-98% protection of the individual given 3 doses. Many western countries have eradicated polio by using IPV alone or along with OPV. IPV has no risk of VAPP. Thus a schedule of IPV and OPV is suggested as follows: Birth: OPV 6 Weeks: IPV 10 Weeks: IPV 14 Weeks: IPV 15 months: IPV 5 years: IPV Back to All Questions

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

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