The dosing of montelukast is determined by plasma concentration levels of the drug. Studies in children have demonstrated that The plasma concentration profile of montelukast following administration of the 10-mg film-coated tablet is similar in adolescents ³ 15 years of age and young adults. The 10-mg film-coated tablet is recommended for use in patients ³ 15 years of age.

The mean systemic exposure of the 4-mg chewable tablet in pediatric patients 2 to 5 years of age and the 5-mg chewable tablets in pediatric patients 6 to 14 years of age is similar to the mean systemic exposure of the 10-mg film-coated tablet in adults. The 5-mg chewable tablet should be used in pediatric patients 6 to 14 years of age and the 4-mg chewable tablet should be used in pediatric patients 2 to 5 years of age.