Levamisole is a synthetic imidazothiazole derivative, and was originally used as an antihelminthic to treat worm infestations in both humans and animals.Levamisole is used to treat malignant melanoma (a type of skin cancer), and in combination with fluorouracil it is used to teat a particular type of colon cancer. In children it is used to treat nephrotic syndrome and is used in dose of 2.5mg/kg/alt day. It is given only in children with steroid responsive frequent relapser with relapses that are infection induced. The mechanism of action of its immunomodulatory effect is not known.