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In the neonate, sepsis is the most frequent cause and later biliary atresia (BA) is seen in as many as 75% of cases with conjugated hyperbilirubinemia. The list of causes is given below:
Infective, Inherited disorders such as Niemann-Pick Type C, Galactosemia, Alpa-1 antitrypsin deficiency, Biliary Hypoplasia (Syndromic), Cholestasis with actin and microfilament accumulation, Progressive intrahepatic cholestasis, Trisomy 13, Trisomy 18, Trisomy 21 etc.
Since the mother had TORCH infection in pregnancy, one should rule out TORCH in the baby
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