4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
Hi Doctor, My son is 1.5 months old. He is 5 weeks pre-term baby. He has conjugated jaundice. We are Indian and now in UK. Recently Liver & Kidney had been scanned and found normal and no obstraction of biliary tree. So what should we do next. His mum was affected with TORCH infection in her pregnancy. Please help. I am not in this profession but seeking help.
Answer
In the neonate, sepsis is the most frequent cause and later biliary atresia (BA) is seen in as many as 75% of cases with conjugated hyperbilirubinemia. The list of causes is given below:

Infective, Inherited disorders such as Niemann-Pick Type C, Galactosemia, Alpa-1 antitrypsin deficiency, Biliary Hypoplasia (Syndromic), Cholestasis with actin and microfilament accumulation, Progressive intrahepatic cholestasis, Trisomy 13, Trisomy 18, Trisomy 21 etc.

Since the mother had TORCH infection in pregnancy, one should rule out TORCH in the baby.
 
 
 
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Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
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