4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
A 3 year old boy present with 3 swelling over the scalp, biopsy of which is proved as langerhans cell histiocytosis. He also has involvement of left optic nerve with loss of vision in that eye. He also has diabetes insipidus. LFT-normal Bone marrow is normal. Study of peripheral smear is normal. Study revealed iron deficiency anemia. When is chemotherapy indicated, is their need to emergency radiotherapy to orbit?
Answer
After complete evaluation, patients with disease involving a single bone and, in some instances, patients with disease involving multiple lesions and multiple bones are managed with local therapy. This involves surgical curettage for patients whose lesions are in easily accessible, noncritical locations. Localized radiotherapy using megavoltage equipment is usually given to patients at risk for skeletal deformity, visual loss secondary to exophthalmos. Low-risk patients > 2 yr old with single-system disease, either in a single bone or multiple bones, frequently require local therapy and little if any systemic therapy. However, failure to thrive or a persistently elevated ESR may indicate significant systemic disease.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
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