4th Pediatric Infectious Diseases Conference
 
 
Home  Back   ISSN 0973 - 0958
 
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Specialist Answers
Question
8 year old male patient known case of retro viral positive , whose count was only 5 was put on zidovudine,lamivudine and stavudine for 2 years. I knew that the combination of zidovudine and stavudine should not be used..so immediately I changed to zidovudine , nevirapine and lamivudine. I wanted to change 2 drugs but I changed 1 drug only as patient could not afford. Patient was alright for 1 year but now he is loosing weight from 25 to 21 now..But is symptom free. Please suggest me what am i suppose to do...
Answer
Dr Ira Shah replies:
You must rule out the following:
Treatment failure. Do a CD4 count and see for clinical as well as immunological failure.
2. Rule out drug reaction. Since the child was on zidovudine and stavudine together and is presently on AZT and 3TC, then rule out metabolic problems such as hypertriglyceridemia, hypercholesterolemia, lipodystrophy, diabetes mellitus, lactic acidosis and hepatic steatosis.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
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