Effect Of Extra Dose of Hepatitis B Vaccine

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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Question
A 4 month male baby has taken 4 doses of hepatitis-b vaccine. one after birth, next at 6 wks,10 wks,& 15 wks. what will happen as he taken an extra dose of hepatitis-b vaccine? What will be the best management in gerd(pediatric age)? Should mosapride be used in a child of 2 years 6 months? Should flu-vaccine be given to all children?
Answer
Regarding the first question of 4 doses of Hep B vaccine given to a baby,it will not cause any adverse effect.In fact the recommendation by WHO for countries where perinatal transmission is high is to start first dose at birth specially for India and to follow it up with 6 and 14 weeks or 6,10 and 14 weeks schedule.The last schedule is an accepted one specially in country program situation where it may not be possible to remember to give 2 doses following the 0 dose by a health worker along with DPT and OPV. There may not be immunization card always available with the parents.Hence 4 doses schedule can be followed. GERD in infants can be managed by thickened feeds, propped up position while feeding, prokinetic agents under the guidance of a gastroenterologist and if severely symptomatic by surgery. Regarding Flu vaccine, it should not be given routinely to all infants since we are not sure about the serotype prevalent in our country and the efficacy of the vaccine is also about 60% only. The live attenuated vaccine is manufactured only in China and has been found to be safe and more efficacious with almost 100%seroconversion.At present it is used only for Chinese market.However the vaccine is shortly going to be marketed by a Koren company.It will take sometime for this vaccine to come to India since the vaccine is not WHO certified and a bridging clinical seroconversion study will be required before the vaccine marketed in India. Back to All Questions

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