4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
A woman is hiv positive. She has delivered 4 days back. Postpartum her tuberculin test positive. Hence she was further screened for kochs. On USG she is having abdominal lymphadenopathy with splenic microabscesses.Physician says that it is a case of abdominal kochs.sputum is negative. CHEST X-RAY IS NOT SUGGESTIVE OF pulmonary kochs. Physician says that though it is not an open case. It can be disseminated kochs. AND sputum report can be false negative. Should we start prophylactic antitubercular therapy to the baby considering it as a case of contact mother is going to breast fed the baby. We have similar case i.e. similar finding but whose afb culture came positive 3 weeks later.
Answer
If a pregnant woman with active pulmonary tuberculosis is sputum negative during the last three months of gestation, the risk to infant is negligible. However since the mother is HIV infected and has abdominal kochs with splenic microabscesses, then she may have occult pulmonary TB that may be not seen on the x ray chest in an immunosuppressed state. In such a situation, it would be better to screen the child for TB by doing an x ray chest and a Mantoux test and if suggestive of TB,AKT would be needed. If negative, one may consider INH prophylaxis for the child in view of strong suspicion.
 
 
 
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