4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
An 8 year old male child, resident of Aligarh presented to us with recurrent fever for the past 3 years,3 episodes of jaundice in the last 3 years each lasting for 15 days and swelling in abdomen for past 3 days. No h/o bleeding from any site,BT,urinary or bowel,neurological complaint. On examination he had severe pallor, icterus with no signs of liver failure other than ascites. Liver span was 8 cm, spleen was 9 cm palpable and ascitis present. Hemogram revealed pancytopenia,LFT and PT, PTTK raised, S.Albumin decreased. Patient. was given BT and FFP, LFT and Coagulation profile became normal. VIRAL Hepatitis serology was negative.USG abdomen revealed normal liver, splenic collaterals at hilum,and ascites. Upper GI Endoscopy was normal and KF Ring negative. WHAT IS THE LIKELY DIAGNOSIS?
Answer
Rule out autoimmune liver disease. Also which viral markers have been done? Have you ruled out EBV and CMV? What is the pancytopenia due to ? Is it due to hypersplenism or bone marrow suppression? If due to bone marrow suppression, a bone marrow exam will also be useful. Once the acute liver cell failure resolves, a liver biopsy will be useful.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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