4th Pediatric Infectious Diseases Conference
 
 
Home  Back   ISSN 0973 - 0958
 
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Specialist Answers
Question
Dear Sir, Can we switch to intramuscular Arteether after giving intravenous Quinine for 2 or 3 days in Chloroquin resistant falciparum malaria?
Answer
As a response to increasing levels of resistance to antimalarial medicines, WHO recommends that all countries experiencing resistance to conventional monotherapies, such as chloroquine, amodiaquine or sulfadoxine-pyrimethamine, should use combination therapies, preferably those containing artemisinin derivatives (ACTs - artemisinin-based combination therapies) for falciparum malaria.
WHO currently recommends the following combination therapies (in alphabetical order)for chloroquine resistant malaria:

artemether/lumefantrine
artesunate plus amodiaquine (In areas where the cure rate of amodiaquine monotherapy is greater than 80%)
artesunate plus mefloquine (Insufficient safety data to recommend its use in Africa)
artesunate plus sulfadoxine/pyrimethamine (In areas where the cure rate of sulfadoxine/pyrimethamine is greater than 80%).
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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