4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
If you are given a choice between exchange transfusion and immunoglobulins as therapeutic option in a neonatal case of severe septicemia- 1.which one you will opt for? 2.what is the frequency/or duration/dosage that you will give for. 3.what is your clinical experience regarding this?
Answer
Since you have asked for a personal opinion, I usually use IVIG as compared to exchange transfusion. I find newborns usually to be in a state of hypogammaglobulinemia (they may have maternally transmitted antibodies but they are still not producing enough of their own antibodies). Also exchange transfusion has its own set of problems. The dose would be 400mg/kg one dose.
However, if the child is neutropenic, G-CSF can be considered.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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