4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
What is refeeding syndrome? What is underlying pathogenesis,clinical manifestations and Treatment?
Answer
Refeeding syndrome occurs when previously malnourished patients are fed with high carbohydrate loads, the result is a rapid fall in phosphate, magnesium and potassium, along with an increasing ECF volume, leading to a variety of complications.

The delivery of glucose, either enterally or parenterally, as part of a feeding strategy, can cause a huge increase in the circulating insulin level. The patient struggles to cope with converting to exogenous fuel sources. There is rapid uptake of glucose, potassium, phosphate and magnesium into cells. The serum concentration of these agents falls dramatically. Also due to cortisol secretion there is water and sodium retention that leads to increased ECF volume. It is also known as sugar baby.
Treatment would be to start feeds slowly and being aware of this entity thus preventing it. Supplementation with phosphate may help to prevent it.
 
 
 
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Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
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