Child With White Hair Problem

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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Question
A 11 year old child came to OPD with scattered white hair and no other complain, His elder brother is positive FH, What is the differential diagnosis? What is investigation needed? What is syndrome associated with white hair?
Answer
White/Grey hair in childhood is known as "Premature graying". Premature graying in children is usually genetically programmed - If the parents or grandparents had premature graying, the children may follow suit. The time and speed of gray hair onset is due in part to genetics, and early onset gray hair development can run in families. Very occasionally, a few gray hairs can develop in children as young as 8 years and yet it indicates nothing other than an early onset of the gray hair that we all develop with increasing age. Typical gray hair first develops at age 34.2 +/- 9.6 years in Caucasians while for Black people the average age of onset is 43.9 +/-10.3 years. Certain drugs, herbs and supplements -- including vitamin E are also known to cause graying. Smoke, even second hand smoke, has been linked to premature gray hair. Some diseases cause prematurely gray hair, such as pernicious anemia, hyper/hypo-thyroidism, osteopenia, Progeria, Werner's syndrome children, Book's syndrome, Cri du Chat syndrome, neurofibromatosis and tuberous sclerosis can all cause gray hair in children. Chediak-Higashi is a rare childhood autosomal recessive disorder characterized by immune deficiency; partial oculocutaneous albinism; easy bruisability and bleeding. Back to All Questions

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