4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
Should we give thalassemic patient Folic acid? (why)? why do you give vitamin C?
Answer
Folic acid is required as there is increased RBC turnover due to ineffective erythropoiesis. This leads to folic acid deficiency.

Ascorbic acid deficiency increases insoluble iron (hemosiderin). Vitamin C helps in conversion of hemosiderin into ferritin from which iron can be chelated. High doses of Vitamin C can lead to increased free radical reaction and lipid peroxidaton resulting in tissue damage and rapid cardiac decompensation and even death. Addition of vitamin C 100 mg daily prior to DFO therapy increases iron excretion. 60% of DFO chelated iron is excreted in urine, and 40% in stool.

Read the article on THALESSEMIA on www.pediatriconcall.com.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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