4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
This is regarding anti-tubercular therapy. We have been taught that pyridoxine supplementation is not required in children when they get INH. But nelson has mentioned that pyridoxine may be required to be supplemented in 1-HIV infected children 2-Breast fed infants 3-children taking inadequate diet, if we consider these facts then a significant number of pediatric patient will require pyridoxine. Whereas none of the above said children we have prescribed pyridoxine. Kindly clarify.
Answer
To reduce the risk of drug-related peripheral neuropathy with isoniazid therapy, pyridoxine may be co-administered in all children six years of age and older. In younger children, if there is no malnutrition and dietary intake is good, then no supplement is needed as incidence of neuropathy is less. Pyridoxine administration should also be considered in patients who have conditions in which neuropathy is common (e.g., malnutrition, HIV infected children and patients on anticonvulsants).
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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