4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
Dear sir, can we do something as medical treatment of cryptorchidism?
Answer
Administration of systemic testosterone is minimally effective in achieving testicular descent because the process depends on a paracrine effect--high local levels of testosterone that cannot be achieved systemically. Using gonadotropins to stimulate the testicle to produce testosterone may help patients to achieve these high local levels.
In the United States, the only hormone labeled for the treatment of cryptorchidism is HCG, which is administered intramuscularly. Administration of 1,500 to 2,500 U two times per week for four weeks may be used.

Ref:
Rajfer J, Walsh PC. Hormonal regulation of testicular descent: experimental and clinical observations. J Urol 1977;118:985-90.

Colodny AH. Undescended testis--is surgery necessary? [Editorial]. N Engl J Med 1986;314: 510-1.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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