4th Pediatric Infectious Diseases Conference
 
 
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Hand,Foot and Mouth Skin Diseases in Children
Hand,Foot and Mouth Skin Diseases in Children
Hand,Foot and Mouth Skin Diseases in Children
Hand,Foot and Mouth Skin Diseases
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SKIN PROBLEMS AND TREATMENT IN CHILDREN
Hand,Foot and Mouth Skin Diseases
Hand,Foot and Mouth Skin Diseases in Children
Nikhil Thatte
Medical Science Department, Pediatric Oncall, Mumbai

Differential Diagnosis

Herpangina, Herpetic gingivostomatitis, Aphthous stomatitis, Stevens-Johnson's syndrome are some of the conditions which need to be differentiated from HMFD.


Typically, a clinical evaluation is sufficient to diagnose HFMD. Lab tests which may prove useful are:

HFMD Investigations   Virus isolation - Swabs taken from the vesicles, ulcers or stool can be utilized for isolating the virus. It can then be cultured on viral tissue media or inoculated into mice to obtain a larger sample for demonstration
HFMD Investigations   Serologic tests:

• Acute phase : Neutralizing antibodies can be detected;
• Convalescent phase - For retrospective diagnosis, complement-fixing antibodies can be detected

HFMD Investigations   PCR can be used to distinguish between coxsackie virus A16 and enterovirus 71(6). It has prognostic significance. The usefulness of this technique lies in the fact that epidemics caused by enterovirus 71 tend to be more severe and are associated with more complications and fatalities.

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