Dr Neha Bansal

Signs & Symptoms : May start with ocular symptoms, though long term complications rarely occur. Oral mucosa is most commonly involved with ulcerations and blister formation (1, 2) and skin blisters show Nikolsky sign (peeling of epithelium on tangential pressure).(1) Milder form known as Phemphigus foliaceous affects the more superficial layer and the blisters crust over the face, upper chest and usually don't involve the mucosa.(1, 3) It should be considered in cases of chronic mucositis in children and adolescent population.

Age groups affected : Usually affects older age group (40-60 yrs) and is rare in children. However, cases have been reported. A transient form is seen in neonates of affected mothers. It is most commonly seen in Ashkenazi Jewish population.(1, 2)