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PATIENT INFORMATION ABOUT BILIARY ATRESIA
What medicines may my baby need and why are they given?
The medicines needed will depend upon your child’s condition and progress but some commonly used are:

    • Antibiotics – After the operation a course of antibiotics is initially given by "drip" and completed by mouth. They are used to reduce the risk of infection spreading from the gut into the liver. Further courses will be prescribed as required.
    • Vitamins – Additional vitamins are necessary because poor bile flow can reduce absorption of vitamins. Some may need to be given by injection.
    • Phenobarbitone – This may be given to increase the flow of bile. As it may make your baby sleepy at first it is usually given in one dose a day, in the evening.
    • Cholestyramine – This comes in the form of a powder in individual sachets. Each sachet is mixed with water and given in liquid form. This may be given to improve liver function and remove substances which may otherwise cause the skin to itch. Cholestyramine can affect the absorption of some drugs, especially vitamins. Therefore, with babies it is best to give some at each feed time except when vitamins are given. As your baby becomes older and manages larger volumes the daily dose of Cholestyramine can be given all at once or split into two. For a toddler or an older child needing Cholestyramine, it is best given in one or two doses away from the main meal times and vitamins. Always leave two hours between giving Cholestyramine and vitamins.
    • Sprironolactone – This may need to be given to help your baby get rid excess fluid which otherwise collects in the abdomen and is called ascites. It is not needed in all cases.
    • URSO – This drug may be given at the onset of feeding after Kasai. It is thought to help promote the flow of bile.
    • Ranitidine – It is common to find stomach irritation after any type of abdominal operation and this drug may be given to help alleviate this problem.
If your baby/child needs medicine to reduce a temperature, remember aspirin, and drugs containing aspirin, must not be given; it is safer to sponge your baby with lukewarm water but if this does not work use paracetamol. Ibuprofen should not be given.

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Last created on 21-02-2001
Last updated on 18-11-2006

 


 
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