4th Pediatric Infectious Diseases Conference
 
 
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Endocrine Problems in Children Encyclopedia
Endocrine Problems in Children Encyclopedia
Endocrine in Children Encyclopedia
Endocrine Problems in Children Encyclopedia
Endocrine Problems in Children Encyclopedia
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Insulin Therapy
INSULIN THERAPY
Very long acting: Lantus (Fig.7): Lantus is newer insulin, which works for 24 hrs. The chemical structure of Lantus makes it to be released steadily and continuously in the body, mimicking almost the basal physiological secretion of Insulin. It is the only long acting insulin which is clear and cannot be mixed up with any other insulin.

Regular insulin, Lispro and Aspart are only clear insulins or solution of insulin. Regular insulin modified with addition of protamine and zinc (NPH) or zinc alone (Lente, Ultralente) to prolong duration of action of insulin are cloudy white suspensions.

Lispro is an insulin analog identical to human insulin except for the reversal of two amino acids, lysine and proline, on the B chain.

Fig 7: Peak and Duration of Action of Very Long Acting Insulins

Peak and Duration of Action of Very Long Acting Insulins

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