YELLOW FEVER VACCINE - Immunization
 
YELLOW FEVER VACCINE
Last Updated : 4/13/2016
Sayenna Uduman
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Spectrum of clinical illness
Clinical presentation varies in severity from asymptomatic to fatal. When symptomatic, YF is typically characterized by an acute onset of an undifferentiating febrile flu-like illness. In about 85% of cases, the disease resolves when the acute symptoms subside. For others, after a brief remission lasting anywhere between hours to a day, symptoms worsen and the disease advances, eventually leading to renal failure, hemorrhagic symptoms, and thrombocytopenia. Treatment is symptomatic and supportive. The WHO estimates, an estimated 200,000 people become infected each year, with up to 30,000 deaths annually. Older adults and those with compromised immune systems are most at risk for serious complications.

Risk factors for a traveler acquiring YF disease:
This depends upon various factors that would include: immunization status, use of personal protection measures against mosquito bites, travel history & location, duration of exposure, local rate of virus transmission and activities while travelling. The risk for acquiring YF is low for most travelers, particularly those staying in highly developed major urban areas.

References

Contributor Information and Disclosures

Sayenna Uduman
MD, FAAP Visiting Professor, Infection Control Committee & ID Division of the KIMS
Thiruvananthapuram, Kerala, India


First Created : 4/13/2016
Last Updated : 4/13/2016

References

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