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NUTRITION IN CHILDREN
EFFECTS OF BIFIDOBACTERIUM LACTIS HN019 AND PREBIOTIC OLIGOSACCHARIDE ADDED TO MILK ON IRON STATUS,
ANEMIA, AND GROWTH AMONG CHILDREN 1 to 4 YEARS OLD
Source: Source: J Pediatr Gastroenterol Nutr. 2010 Sep;51(3):341-6
Undernutrition is the major underlying cause of 35% of child deaths and 11% of the global burden of disease among children younger than 5 years of age and a major attributable risk factor for growth faltering and anemia. Developing countries in the southeast Asia region have a high burden of undernutrition, with approximately 51% of Indian preschool children experiencing stunting and 75% experiencing iron-deficiency anemia. Recent community-based randomized controlled trials have provided evidence that consumption of probiotic-supplemented formula or lactobacilli-acidophilus- fortified yogurt resulted in significantly accelerated growth of undernourished as well as adequately nourished preschool children. This community-based double-masked, controlled trial was carried out in a periurban 624 children in Sangam Vihar, a resettlement colony in New Delhi between April 2002 and 2004 to evaluate the effect of Bifidobacterium lactis HN019 intervention for one year and prebioticfortified milk on iron status, anemia, and growth among 1- to 4-year-old children. Children were randomly allocated to B lactis HN019 and prebiotic-fortified milk group (n = 312) and to control milk group (n = 312). Both study groups were similar at baseline. Compliance was high (>85%) and did not vary by intervention groups.
Results: Compared with the consumption of control milk, consumption of probiotic milk resulted in a 45% lower risk of being anemic and iron deficient. The mean weight velocity among children consuming probiotic milk was higher than that in children consuming control milk by 0.13 kg/year. The authors concluded that preschoolers, who are usually fed milk, can be easily fortified for delivery of probiotics which may help improve their health.
Undernutrition is the major underlying cause of 35% of child deaths and 11% of the global burden of disease among children younger than 5 years of age and a major attributable risk factor for growth faltering and anemia. Developing countries in the southeast Asia region have a high burden of undernutrition, with approximately 51% of Indian preschool children experiencing stunting and 75% experiencing iron-deficiency anemia. Recent community-based randomized controlled trials have provided evidence that consumption of probiotic-supplemented formula or lactobacilli-acidophilus- fortified yogurt resulted in significantly accelerated growth of undernourished as well as adequately nourished preschool children. This community-based double-masked, controlled trial was carried out in a periurban 624 children in Sangam Vihar, a resettlement colony in New Delhi between April 2002 and 2004 to evaluate the effect of Bifidobacterium lactis HN019 intervention for one year and prebioticfortified milk on iron status, anemia, and growth among 1- to 4-year-old children. Children were randomly allocated to B lactis HN019 and prebiotic-fortified milk group (n = 312) and to control milk group (n = 312). Both study groups were similar at baseline. Compliance was high (>85%) and did not vary by intervention groups.
Results: Compared with the consumption of control milk, consumption of probiotic milk resulted in a 45% lower risk of being anemic and iron deficient. The mean weight velocity among children consuming probiotic milk was higher than that in children consuming control milk by 0.13 kg/year. The authors concluded that preschoolers, who are usually fed milk, can be easily fortified for delivery of probiotics which may help improve their health.
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