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ISSN 0973 - 0958
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NUTRITION IN CHILDREN
USE OF A FERMENTED DAIRY PROBIOTIC DRINK CONTAINING LACTOBACILLUS CASEI (DN-114 001) TO DECREASE THE RATE OF ILLNESS IN KIDS : THE DRINK STUDY A PATIENT - ORIENTED, DOUBLE-BLIND, CLUSTER-RANDOMIZED, PLACEBO-CONTROLLED, CLINICAL TRIAL
Source: Eur J Clin Nutr. 2010 May 19. [Epub ahead of print].
Abstract
This is a double blind randomized controlled trial to determine whether daily intake of a milk product that contains probiotic strain Lactobacillus casei DN-114 001 in healthy children could reduce the incidence of common infectious diseases (CIDs) and the change of behavior because of illness in children. This study was conducted by Department of Family Medicine at Georgetown University Medical Center in Washington, DC metropolitan area. 638 children from day care centers and schools aged 3-6 years of age were includes in the trial. Patients were randomised to either receive the milk product containing the probiotic strain or placebo with no live cultures for 90 consecutive days. It was found that the rate of change of behavior because of illness was similar among both probiotic and control groups. However, the incidence rate for infections in the probiotic group was 19% lower than that of the control group (P=0.046) predominantly in the gastrointestinal infections suggesting benefit for long term use in healthy children.
Abstract
This is a double blind randomized controlled trial to determine whether daily intake of a milk product that contains probiotic strain Lactobacillus casei DN-114 001 in healthy children could reduce the incidence of common infectious diseases (CIDs) and the change of behavior because of illness in children. This study was conducted by Department of Family Medicine at Georgetown University Medical Center in Washington, DC metropolitan area. 638 children from day care centers and schools aged 3-6 years of age were includes in the trial. Patients were randomised to either receive the milk product containing the probiotic strain or placebo with no live cultures for 90 consecutive days. It was found that the rate of change of behavior because of illness was similar among both probiotic and control groups. However, the incidence rate for infections in the probiotic group was 19% lower than that of the control group (P=0.046) predominantly in the gastrointestinal infections suggesting benefit for long term use in healthy children.
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