Hematological Disorders in Children

Hematological Disorders

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Hematologic Disorders are diseases which primarily affect the blood.

Anemia - Iron Deficiency and Health Consequences

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Iron deficiency is an end result of a long period of negative iron balance mainly due to poor dietary availability, rapid growth and blood loss.

Anemia - Approach to Child with Iron Deficiency Anemia

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Anemia is defined as reduction in the oxygen carrying capacity of blood, as observed by reduced levels of hemoglobin concentration and red cell mass (Hematocrit) leading to tissue hypoxia.

Anemia - Approach to Child with Anemia

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There are four basic causes of anemia - loss, destruction, sequestration and hypoproduction.

]]>There are four basic causes of anemia - loss, destruction, sequestration and hypoproduction.

Nutritional Anemia

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Anemia is a major nutritional global problem of immense public health significance, affecting persons of all ages, sex and economic group. It is ranked as the commonest chronic malady of mankind affecting approximately 30% i.e. 1500 million people all over the world.

Anemia - Indicators for Assessment of Anemia and Iron Deficiency in Community

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Anemia is most likely due to iron and/or folate deficiencies. Vitamin B12 deficiency is also common in younger age group. Hemoglobin estimation, peripheral smear and therapeutic response to iron are good time tested tools and should be used first in diagnosis of iron deficiency. In view of high prevalence of anemia to detect iron deficiency community level screening is recommended.

Approach to a Bleeding Child - Hemostasis

2005-05-01T00:00:00.0000000+05:30

Hemostasis is a delicate balance between clot formation, anticoagulation and fibrinolysis and it occurs in the phases.

]]>Hemostasis is a delicate balance between clot formation, anticoagulation and fibrinolysis and it occurs in the phases.

Hemophilia

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Hemophilia is an inherited disorder in which there is inability to form an effective clot and hence causes prolonged bleeding in a patient. It is seen exclusively in males. A person with hemophilia does not bleed faster, only longer.

Guidelines to Detect Congenital Immunodeficiency

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Malignancies, especially lymphomas, others being leukemias and gastric carcinomas, are several fold more frequent in immunodeficient (ID) children.

Red Cell Substitutes

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The demand for blood is always more than its supply. Also with risk of blood borne infections, efforts for finding an artificial substitute for human blood is going on.

Idiopathic Thrombocytopenia Purpura (ITP) in Children

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Probably the most important factor in dealing with the child with ITP is the attitude of the treating clinician. The treatment should be directed at the patient rather than at the platelet count.

Hemoglobin Variants Detection by HPLC (High Performance Liquid Chromatography) Method

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The process of HPLC starts with extraction of analyte of interest for liquid chromatographic process.

Facts about Platelet Transfusion

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Types of Platelets : Random Donor Platelets (RDP) and Single Donor Platelets (SDP).

Hematological Manifestations of Systemic Illness

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A variety of systemic illnesses including acute and chronic infections, neoplastic diseases, connective tissue disorders, and storage diseases are associated with hematological manifestations.

Modern Trends in Management of Thalassemia

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It is a heterogeneous disorder recessively inherited resulting from various mutations of the genes, which code for globin chain of Hb, leading to reduced or absent synthesis of globin chains. When b chain synthesis is affected it is called as b -thalassemia.

Administration of Blood

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Safe transfusion practice begins with correct identification of the intended recipient. Blood samples of the recipient should be identified and labeled properly. Test recipient's blood for ABO Group, Rh type, Coomb's & crossmatch.

Aplastic Anemia : Its Causes and Diagnosis

2006-07-01T00:00:00.0000000+05:30

Aplastic anemia (AA) is a disease characterized by pancytopenia and hypocellular (or fatty) marrow. It is a rather rare disorder, with an annual incidence of about 2-6 per million population. In about 50% of these cases, the etiology is unknown ( Idiopathic Aplastic Anemia ).

Treatment Strategies of Aplastic Anemia

2006-07-01T00:00:00.0000000+05:30

The treatment strategy of Aplastic anemia (AA) is based on consideration of the severity of the disease (i.e. a high probability of demise), data on the response rate to different kinds of treatment options and the natural history of disease.