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  • An 18 month-old boy presented with fever and recurrent generalized tonic convulsions. He was treated with anticonvulsants, antibiotics, and acyclovir. CT brain findings are consistent with ANEC (acute necrotizing encephalopathy of childhood) with brainstem involvement. He was treated with a course of methylprednisolone and IVIG. After 2 weeks, clinically he remains in an encephalopathic state.  What are the role of steroids and IVIG and when is the practical time to use them in patients with ANEC?
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Question of the Week

Q. An 18 month-old boy presented with fever and recurrent generalized tonic convulsions. He was treated with anticonvulsants, antibiotics, and acyclovir. CT brain findings are consistent with ANEC (acute necrotizing encephalopathy of childhood) with brainstem involvement. He was treated with a course o ...
Answer

Teaching Files/ Grand Rounds

A 7-year-old boy presented with abdominal pain for 2 days. He was diagnosed to have extrahepatic portal hypertension with portal cavernoma at the age of 1 year. At that time, he had hematemesis and malena. However, colonoscopy and esophagogastroscopy ...
What is the cause of duodenal and jejunal polyps?
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Diagnostic Dilemma

A 2½ months old boy born of non-consanguineous marriage presented with fever and staring look. He was admitted in a hospital and CSF was suggestive of pyomeningitis. He was treated with IV antibiotics. However on 7th day of illness was found to have hypernatremia (serum sodium = 184 mEq/L). He was g ...
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Poll

Q. The data, released by South Africa's National Institute for Communicable Diseases (NICD), shows that 52 infants under age 2 were a..
  • Pediatric vaccinations & testing should be prioritized.
  • No action should be taken till we gather more data on the clinical presentation, severity and to better understand the epidemiology of the disease in children with Omicron variant.
  • Travel restriction should be implemented to protect pediatric age groups.
  • Implementation of nonpharmaceutical interventions, discourage community and mass gatherings involving young people
  • To increase maternal vaccination, vaccination among eligible adolescents, adults who encounter infants/young children especially with underlying conditions placing them at increased risk of infection
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