Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis

Neha Bansal
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Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis - Treatment
It is considered a dermatological emergency and is treated aggressively. It had high mortality and morbidity. (2, 4) Supportive care in the form of IV fluids and other management similar to that of a burn's patient is given. No certain line of therapy exists and various treatment options are available. The specific infections need specific antibiotics (like diagnosed mycoplasma needs doxycycline). Various drugs like prednisolone and cyclosporine have been used to halt the disease progress. (5) Anti TNF-alpha drugs like infliximab have shown positive results. (5) Off label use of high dose IVIG has been reported with certain benefits. (5)However, its use as an accepted line of therapy is still uncertain. (3) Plasmapheresis seems to be a good alternative treatment option. (5)


References
Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis 1/24/2013
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