Dr. Ira Shah | History of Management of Infectious diseases
Description
Changing trends in diagnosis and management of pediatric infectious diseases
Infectious diseases - leading cause of death | The top ten leading causes of death | Infectious diseases since time immemorial | Infectious diseases epidemics | Plague epidemic - changed the face of greek civilization - 430 BCE | Pladue diseases in ancient times | Persistent epidemics - spanish flu early 1900's | H1N1 influenza 2009 | WHO report (2007) | Ancient Harappan civilization - India 3300-1300 BCE | Concepts of infectious diseases | Sushruta Samhita - 6th century BCE | Charak Samhita | Alexandra the Great - History changes (356 - 323 BC) | Period of exploration | Andaman islands | Effect of infectious diseases on human genes | Fracastoro speaking about germs in 1500 AD | Miasma theory (19th century) | Lgnaz semmelweis (1847) | John Snow (1849) | Louis Pasteur (1860-1864) | Joseph Lister (1870) | Robert Koch (1884) | Microscope and germs | Emerging treatment strategies in infectious diseases | Dicovery of antibodies | Monoclonal antibodies | Elisa | Alexander Fleming (1929) | Word of caution | Subsequently new antibiotics discovered | Emergence of resistance | Time line of antibiotic resistance | Immunization - History | Small pox vaccination | other vaccines | Molecular genetics and vaccinology | Revolutionary molecular technologies | DNA and PCR | Syndromic testing of infectious diseases | Respiratory panel- Simultaneous testing for 20 of the most common pathogens involved in RTI | GI panel - 22 target pathogens at once | Sepsis panel - 24 pathogens and 3 antibiotic resistance genes | 1990 - 2003 human genome project | Haplotype structure of parasites within Mls | SNPs help to predict tendency to a disease | Emerging Infections | Newer diseases - HIV | Antiretroviral drugs | Era of monotherapy | Early 1990's - era of dual therapy | Late 1990's - Era of triple therapy | Emerging infections | Immune system | Infections and immune system | Congenital immunodeficiency | Treatment options | ID in special situations | Emerging trends in diagnosis and drugs | Emerging Trends in treatment - evidence based | Emerging trends in prevention | Emergence of Multiresistant Pathogens | Emergence of old drugs and drugs used in adults | So where are we headed? | Infectious diseases fellowships | B J Wadia Hospital for Children |
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