Anti-histaminics
 
print
They antagonize the effects of histamine. Commonly used preparations are antistine, histantin, chlorphenirmine, promethazine
Route :
ingestion, inhalation or injection
Fatal Dose :
1gm
Mechanism of action :

Clinical Picture :
Occur due to excitation and depression of CNS • dryness of mouth, nausea, vomiting, drowsiness, headache, blurred vision, urinary retention and nervousness • agranulocytosis and aplastic anemia • in large doses, fixed dilated pupils, disorientation, hyperreflexia, tremors, nystagmus, convulsions
Treatment :
• stomach wash • Physostigmine: 0.5mg to 2mg i.v. every hour till reversal of symptoms occurs • diazepam i.v.
ask doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.