Aluminum-phosphide
 
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They are white or grey tablets with garlicky odor.
Route :
Ingestion or inhalation
Fatal Dose :
one tablet (3gm)
Fatal Period :
24 hours
Mechanism of action :
It is due to phosphine gas {PH3} gas released on contact with gastric Hcl. Phosphine inhibits respiratory chain enzymes and has cytotoxic action.
Clinical Picture :
• dizziness • vomiting • diarrhea • respiratory distress • cyanosis • cardiac arrhythmia • circulatory failure • convulsions
Treatment :
• Gastric lavage with sodium bicarbonate • Activated charcoal • Antacids reduce absorption of phosphine • Magnesium reduces organ toxicity, hypomagnesemia and arrhythmia`s • Symptomatic
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