Grand Rounds

A mother with bad obstetric history - Is it due to cytomegalovirus?


Suhani Jain1, Ira Shah2
1Grant Government Medical College, Sir JJ Group of Hospitals, Mumbai, India, 2Consultant in Pediatric Infectious Diseases, Levioza Health Care, Mumbai, India

Address for Correspondence: Suhani Jain, Flat number 402, Ramdeo Arise, Behind Hotel Airport Centre Pt, Wardha Road, Nagpur-440025. Email: suhani2208@gmail.com


Keywords: Bad obstetric history, Cytomegalovirus, TORCH infections

Clinical Problem:
A 32-year-old pregnant female at 9.5 weeks of gestation presented for ruling out fetal deaths due to intrauterine infection. She has a bad obstetric history with a medical termination of pregnancy (MTP) a year ago at 5.5 months of gestation due to congenital malformations in the baby. She also had a spontaneous abortion at 14 weeks of gestation 6 months ago. While screening for infections in the first pregnancy , it was found that Rubella IgG was positive (73.4 AU/ml), varicella zoster virus (VZV) IgG was positive (1.01 AU/ml) as well as cytomegalovirus (CMV) IgG was raised. For the second pregnancy , Rubella IgG was 117 AU/ml , VZV wasn’t detectable and CMV IgG was 49 AU/ml. For present pregnancy, she was followed up with IgG levels of rubella , VZV and CMV (Table 1).

Table 1. Serial TORCH titres in current pregnancy.
Gestational age (months) Rubella IgG (AU/ml) Varicella zoster IgG (AU/ml) Cytomegalovirus (CMV) IgG (AU/ml) CMV avidity
7 weeks 67 negative 218  
11 weeks     190.45 0.91 (high)


Is the lady’s bad obstetric history due to CMV infection?


Previous Grand Rounds View All

I
Is it BCGiosis or disseminated Tuberculosis?
Tsering Yangchen, Ira Shah
An 11 months old girl presented with gradually increasing left axillary swelling for which she underwent an incision & drainage of the pus 1 week ago. Pus wall histology showed granulomatous inflammat....
S
Salmonella enterica meningitis in a neonate
Suhani Jain, Ira Shah
A 15-day-old boy presented with a complaint of poor feeding and fever for two days. The child was previously alert and was breastfeeding normally since birth. He was born at full term by vaginal deliv....
A
A child with Budd Chiari syndrome and recurrent thrombosis
Suhani Jain, Ira Shah
A 10-month-old girl presented with ascites. At 3 months of age, she had ascites and was diagnosed to have Budd Chiari syndrome (BCS) due to acute thrombosis of Middle and Right Hepatic veins (MHV and....
P
Pseudohypoaldosteronism Secondary to Urinary Tract Infection in a Premature Newborn Baby
Samet Benli, Erdal Taşkın, Mustafa Aydın
Upon the detection of sodium 120 mmol/L and potassium 8.8 mmol/L in the routine examinations taken on the 93th day of hospitalization of a premature baby born at the 24th gestational week, weighing 70....
R
Recurrent Pinworm Infestation
Suhani Jain, Ira Shah
A 6-year-old boy presented with passing recurrent worms in the stool for three years for which he had been treated with multiple courses of anthelminthics in form of albendazole and mebendazole. Add....
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0