Menu
Disease
A-Z
Health Topics
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
Pediatric Dermatology
View all Topics
Featured Articles
Urticaria (hives) and angioedema
Anal fissure
Penile hygiene
Diabetic ketoacidosis
Anaphylaxis
Skin allergies
Kids Corner
Health and Knowledge with fun.
Drugs &
Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calcualtors
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Equipments
Diagnostic Aid
Get your diffrential
diagnosis.
Consult
& Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric
Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books
& Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME &
Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine
Reminder
Sign In
Diagnostic Dilemma List
Is it Hyper IgM syndrome?
URTI with wheeze
Delayed development with light hair
Purpura Fulminans
Urinary tract infection
Grunting
Diagnostic Dilemma
Home
|
All Discussions
|
Submit Dilemma
Is it Hyper IgM syndrome?
Author:
Pediatric Oncall
Question
A 3 months old boy born of non-consanguineous marriage presented with fever, cough and left focal convulsion for 1 day. On examination he had bulging anterior fontanelle with brisk reflexes and extensor plantar reflex. Other systemic examination was normal. Investigations showed leucocytosis (WBC count = 18,900/cumm) with positive C-reactive protein (192 mg/dl) and CSF revealed 90 cells/cumm with 33% polymorphs and 67% lymphocytes and sugar of 50 mg/dl. His blood culture and CSF culture was negative. He was treated with IV ceftriaxone. On day 10, of IV antibiotics, he developed right shoulder joint arthritis. His antibiotics were then changed to IV vancomycin & meropenem which was given for 42 days. HIV ELISA was negative. Serum immunoglobulins showed elevated IgM and decreased IgG & IgA. He was started on oral trimethoprim-sulphamethoxazole (TMP-SMX) prophylaxis and advised monthly IVIg and bone marrow transplant which parents refused. He continues to have recurrent diarrhea and respiratory tract infections on follow up.
Is it Hyper IgM syndrome?
Previous Discussions
View All
U
URTI with wheeze
Pediatric Oncall
A 2 years old child presented with cold and cough (more at night) for 5 days and breathlessness for 1 day. There is no fever. Mother has recurrent sinusitis and is allergic to dust. There is no contac....
D
Delayed development with light hair
Pediatric Oncall
A 2 years old boy born of non-consanguineous marriage presented with cough and fever for 7 days. There is no history of contact with TB. He also has delayed milestones and is not able to sit, roll ove....
P
Purpura Fulminans
Pediatric Oncall
A 3 years old boy is found to have dry gangrene of right index finger, left little finger and 2nd and 3rd left toe. He had fever for 3 months and an erythematous rash 15 days ago.
U
Urinary tract infection
Pediatric Oncall
A 10 month old girl presented with increased frequency of micturation, pain on passing urine and vomiting for 3 days. There is no fever, oliguria or refusal of feeds. On examination, there is no signi....
G
Grunting
Pediatric Oncall
A 4 months old boy presented with cough for 5 days, fever for 2 days and breathlessness for 1 day associated with refusal of feeds and irritability. There is no altered sensorium or vomiting. On looki....
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
X
Sign In
Disease A-Z
Health Topics
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
Pediatric Dermatology
View all topics
Featured Articles
Urticaria (hives) and angioedema
Anal fissure
Penile hygiene
Diabetic ketoacidosis
Anaphylaxis
Skin allergies
Kids Corner
Drugs & Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calculators
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Eqipments
Diagnostic Aid
Consult & Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric Oncall Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books & Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME & Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine Reminder
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0