Urticaria (Hives) and Angioedema

Mitchell R. Lester
Urticaria (hives) and Angioedema - Abstract
Urticaria and angioedema affect about 20% of the population at some point in their lives. The conditions frequently coexist and commonly reflect the same process occurring at different cutaneous levels.
The differential diagnoses of acute and chronic urticaria differ, with the majority of chronic cases being idiopathic. This article will describe an approach to identifying triggers of urticaria and angioedema and discuss principles of treatment.

CIU: Chronic idiopathic urticaria, chronic spontaneous urticaria
CU: Chronic urticaria/angioedema
LTRA: Leukotriene receptor antagonist
NPV: Negative predictive value
NSAID: Nonsteroidal anti-inflammatory drug
PPV: Positive predictive value
RAST: Radioallergosorbent test
TCA: Tricyclic antidepressant

Urticaria/angioedema are common problems in the pediatric population with a cumulative prevalence of about 20%. Their acuity is frightening to parents, they can be disfiguring, and the itch is distressing but when they occur without other systemic signs or symptoms they are rarely serious.

Pediatricians who understand the differential diagnoses of acute and chronic urticaria/angioedema, take a detailed history, use judicious testing, and apply evidence-based guidelines for treatment are able to reassure parents and families about the usually benign nature of the conditions. The aim of this paper is to provide a framework for the diagnosis and treatment of urticaria/angioedema.

Urticaria (Hives) and Angioedema Urticaria (Hives) and Angioedema 04/04/2016
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