Drug Index

Lactic acid

Mechanism :

Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha hydroxy acids act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. The mechanism(s) by which this is accomplished is not yet known.

Indication :

  • Ichthyosis vulgaris
  • Xerosis

Contraindications :

Contraindicated in those patients with a history of hypersensitivity to any of the label ingredients.

Dosing :

Available as 10% lotion or cream.
Twice daily application to the affected areas and rub in thoroughly.

Adverse Effect :

The most frequent adverse reactions were rash (including erythema and irritation) and burning/stinging. In addition, itching was reported in approximately 5% of patients.

Interaction :

No known drug interactions.

Hepatic Dose :

No dose adjustments are recommended.
01/19/2024 07:19:45 Lactic acid
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