Drug Index

Laronidase

 
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Mechanism :

Laronidase is a recombinant (replacement) form of alpha-L-iduronidase derived from Chinese hamster cells.


Indication :

• Mucopolysaccharidosis I (Hurler syndrome, Hurler-Scheie, and Scheie forms)


Contraindications :

Severe hypersensitivity to laronidase or any component of the formulation.


Dosing :

Infants ≥6 months

IV: 0.58 mg/kg once weekly.


Adverse Effect :

Flushing, venous irritations, chills, skin rash, antibody development, injection site reaction, otitis media, infusion related reactions, hypertension, chest pain, headache, pallor, thrombocytopenia, hyperbilirubinemia, tremor.


Interaction :

No known significant interactions.


07/18/2019 01:49:24 Laronidase
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