Pirbuterol
Mechanism :
Beta-2 receptor agonist with some beta-1 activity.
Indication :
- Asthma Maintenance Treatment
Contraindications :
Hypersensitivity to pirbuterol or any of its components.
Dosing :
<12 years:
Safety and efficacy not established.
>12 years:
1-2 puffs (Each puff-200 mcg) 4-6 hourly; not to exceed 12 puffs/day.
Adverse Effect :
Nervousness, restlessness, hyperglycemia, hypokalemia, tremors, palpitations, tachycardia, cough, headache, dizziness, light headedness, taste changes, vomiting, nausea, paradoxical bronchospasm.
Interaction :
Tricyclic antidepressants: Tricyclic antidepressants increase or decrease effects of sympathomimetics.
Linezolid: Increases effects of pirbuterol by pharmacodynamic synergism.
Hepatic Dose :
No dosage adjustments are recommended.