Immune Thrombocytopenic Purpura in Children

Dr. Priti S. Mehta
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Diagnosis
Bone marrow examination is no longer mandatory to confirm diagnosis of ITP. A careful history, physical examination, complete blood count and review of the peripheral blood smear are the key factors in diagnosing ITP. The routine use of antiphospholipid, antinuclear antibodies, thrombopoeitin levels or platelet parameters is not routinely required in the diagnosis of ITP. A bone marrow examination to rule out other disorders is required in children presenting clinically with fever, bone or joint pain, skeletal or soft tissue abnormalities, non-petechial rash and lymphadenopathy. A family history of low platelets or easy bruising and HIV infection should be asked for. An abnormal haemoglobin level, abnormal WBC morphology or count is not typical of ITP and also requires a bone marrow examination.6 This is to avoid missing leukemias before starting steroids but not required before giving intravenous Immunoglobulin.


References
Immune Thrombocytopenic Purpura in Children Immune Thrombocytopenic Purpura in Children 06/28/2016
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