Drug Index

Aliskiren

 
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Indication :

• Children above 6 years (>20kg) with hypertension. It is a renin inhibitor.


Dosing :

75 mg/day. Max: 150 mg/day.


Adverse Effect :

Diarrhea, cough, rash, increased serum creatinine, hyperkalemia, headache, edema. Hyponatremia.


Renal Dose :

Dose in Renal Impairment GFR (mL/min)
20-50Dose as in normal renal function
10-20Dose as in normal renal function
<10Dose as in normal renal function

Dose in Patients undergoing Renal Replacement Therapies
CAPDUnlikely to be dialysed. Dose as in normal renal function
HDUnlikely to be dialysed. Dose as in normal renal function
HDF/High fluxUnlikely to be dialysed. Dose as in normal renal function
CAV/VVHDUnlikely to be dialysed. Dose as in normal renal function

Hepatic Dose :

No dosage adjustments are recommended.
05/28/2020 02:19:49 Aliskiren
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