Drug Index

Almotriptan

 
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Indication :

• Acute Migraine in children >12 years of age.


Dosing :

>12 years: 6.25-12.5 mg orally at onset of headache. Can repeat after 2 hours. Max dose: 25 mg/day.


Adverse Effect :

Increased sleepiness, dizziness, dry mouth, vomiting, paresthesia, anaphylaxis, blurring of vision.


Renal Dose :

Dose in Renal Impairment GFR (mL/min)
30-50Dose as in normal renal function
10-306.25 mg; maximum daily dose 12.5 mg. Use with caution
<106.25 mg; maximum daily dose 12.5 mg. Use with caution

Dose in Patients undergoing Renal Replacement Therapies
CAPDUnknown dialysability. Dose as in GFR<10 mL/min
HDLikely dialysability. Dose as in GFR<10 mL/min
HDF/High fluxLikely dialysability. Dose as in GFR<10 mL/min
CAV/VVHDUnknown dialysability. Dose as in GFR=10–30 mL/min

Hepatic Dose :

Mild to moderate hepatic impairment: Use with caution. Approximately 45% of almotriptan elimination is through hepatic metabolism. The recommended initial dose is 6.25 mg PO; the maximum dosage is 12.5 mg/day.
Severe hepatic impairment: Use is contraindicated.
05/21/2020 01:56:36 Almotriptan
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