Drug Index

Benzamphetamine

 
print

Mechanism :

Benzphetamine hydrochloride is a sympathomimetic amine with pharmacologic activity like the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure.


Indication :

• Exogenous obesity (short-term)


Contraindications :

Contraindicated in patients with advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hypothyroidism, known hypersensitivity or idiosyncrasy to sympathomimetic amines, and glaucoma. Benzphetamine should not be given to patients who are in an agitated state or who have a history of drug abuse. Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. Should not be used concomitantly with other CNS stimulants.

May cause fetal harm when administered to a pregnant woman.


Dosing :

Not recommended in children under 12 years of age.

≥12 years: 25 to 50 mg PO one to three times daily. Start with once a day and then increase as per response.


Adverse Effect :

Palpitation, tachycardia, hypertension, cardiomyopathy, overstimulation, restlessness, dizziness, insomnia, tremor, sweating, headache, psychotic episodes, depression following withdrawal of the drug, dryness of the mouth, unpleasant taste, nausea, diarrhea, constipation, urticaria, changes in libido.


Interaction :

Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly within 14 days following use of monoamine oxidase inhibitors. Should not be used concomitantly with other CNS stimulants.
Amphetamines may decrease the hypotensive effect of antihypertensives. Amphetamines may enhance the effects of tricyclic antidepressants.
Urinary alkalinizing agents increase blood levels and decrease excretion of amphetamines. Urinary acidifying agents decrease blood levels and increase excretion of amphetamines.


07/15/2019 06:29:30 Benzamphetamine
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0