Drug Index
Synonym :

Vestronidase alfa-vjbk

Mechanism :

Vestronidase alfa-vjbk is a recombinant human beta-glucuronidase (GUS), which provides exogenous GUS enzyme for uptake into cellular lysosomes.

Indication :

  • Mucopolysaccharidosis VII

Contraindications :

No contraindications.

Dosing :

4 mg/kg every 2 weeks.
Limitations of use:
The effect of vestronidase alfa-vjbk on the CNS manifestations of MPS VII has not been determined.
Note: Premedicate with non-sedating antihistamines with/without antipyretics 30 to 60 minutes prior to the start of the infusion.

Adverse Effect :

Skin rash, diarrhea, anaphylaxis, antibody development, peripheral edema, pruritus, swelling at injection site, febrile seizures.

Interaction :

No known significant interactions.

Hepatic Dose :

No dosage adjustments are recommended.
09/28/2020 08:13:58 Beta Glucuronidase
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0