Drug Index

Bimatoprost

 
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Mechanism :

Bimatoprost is a prostamide, a synthetic structural analog of prostaglandin with ocular hypotensive activity. It selectively mimics the effects of naturally occurring substances, prostamides. Bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing outflow of aqueous humor through both the trabecular meshwork and uveoscleral routes. Elevated IOP presents a major risk factor for glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.


Indication :

• Open angle glaucoma or ocular hypertension


Contraindications :

Contraindicated in patients with hypersensitivity to bimatoprost or any other ingredient in this product.


Dosing :

Ophthalmic solution 0.03%

For >16 years of age: 1 drop in the affected eye(s) once daily in the evening.


Adverse Effect :

Conjunctival hyperemia, growth and darkening of eyelashes, ocular pruritus and dryness, visual disturbance, ocular burning, foreign body sensation, blepharitis, cataract, superficial punctate keratitis, eyelid erythema.


Interaction :

Latanoprost: Concurrent use of bimatoprost and latanoprost may result in paradoxical increase in intraocular pressure.


07/18/2019 09:45:11 Bimatoprost
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