Drug Index


Mechanism :

Competes with histamine for H1-receptor sites on effector cells.

Indication :

  • Upper respiratory allergies.

Contraindications :

No contraindications.

Dosing :

2 to <6 years:
1 mg every 4 to 6 hours (Maximum: 6 mg/day)
6 to <12 years:
2 mg every 4-6 hours (Maximum: 12 mg/day)

Adverse Effect :

Angina pectoris, chest tightness, circulatory shock, extrasystoles, hypotension, increased blood pressure, palpitations, tachycardia, Anxiety, ataxia, central nervous system stimulation, chills, confusion, dizziness, drowsiness, abdominal cramps, anorexia, constipation, diarrhea, epigastric distress, Agranulocytosis, hemolytic anemia, hypoplastic anemia, thrombocytopenia, anaphylactic shock, tremor, weakness, dry nose, dry throat, nasal congestion, thickening of bronchial secretions, wheezing.

Interaction :

Acetylcholinesterase Inhibitors: May diminish the therapeutic effect of Anticholinergic Agents.
Aclidinium: May enhance the anticholinergic effect of Anticholinergic Agents.
Anticholinergic Agents: May enhance the adverse/toxic effect of other Anticholinergic Agents.
CNS Depressants: May enhance the adverse/toxic effect of other CNS Depressants.
Gastrointestinal Agents (Prokinetic): Anticholinergic Agents may diminish the therapeutic effect of Gastrointestinal Agents.
Selective Serotonin Reuptake Inhibitors: CNS Depressants may enhance the adverse/toxic effect of Selective Serotonin Reuptake Inhibitors.

Hepatic Dose :

Brompheniramine is metabolized by the liver. Use with caution in hepatic impairment as concentrations of brompheniramine may increase. Dose adjustment may be required.
01/24/2024 18:01:28 Brompheniramine
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